When she was told Custer's troopers had just killed her brother at the Battle of the Greasy Grass (Little Bighorn), Moving Robe Woman wanted revenge. She rode out with the warriors against the Reno detachment and saw Reno and his men take flight across the river.

Hearing that there were more soldiers coming from the opposite direction, she galloped off with the warriors to meet the new threat. Moving Robe Woman took an active part in the final charge against Custer's detachment. She killed two of the troopers, one with a pistol shot to the head, the other by stabbing him with her sheath knife.

The Battle of the Greasy Grass was not the first battle that Moving Robe Woman was involved in. At 17 she was part of a Sioux raid against the Crows in Montana.

Moving Robe Woman followed Sitting Bull into Canada where she stayed for four years before surrendering at Fort Buford, Montana in 1881. She lived out her remaining years on the Standing Rock Reservation, which straddles the border between North Dakota and South Dakota.